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table of contents
  1. Front Matter
    1. About the Text
    2. OpenStax Preface
  2. Chapter 1
    1. What Our Ancestors Knew
      1. The Iceman Treateth
      2. Early Notions of Disease, Contagion, and Containment
      3. The Birth of Microbiology
    2. A Systematic Approach
    3. Types of Microorganisms
      1. Eukaryotic Microorganisms
      2. Helminths
      3. Viruses
      4. Microbiology as a Field of Study
      5. Summary
      6. Review Questions
  3. Chapter 3
    1. Spontaneous Generation
      1. Disproving Spontaneous Generation
    2. Foundations of Modern Cell Theory
      1. Endosymbiotic Theory
      2. The Germ Theory of Disease
    3. Unique Characteristics of Prokaryotic Cells
      1. The Nucleoid
      2. Plasmids
      3. Ribosomes
      4. Inclusions
      5. Endospores
      6. Plasma Membrane
      7. Cell Wall
      8. Glycocalyces and S-Layers
      9. Filamentous Appendages
    4. Unique Characteristics of Eukaryotic Cells
      1. Nucleus
      2. Ribosomes
      3. Endomembrane System
      4. Peroxisomes
      5. Cytoskeleton
      6. Mitochondria
      7. Chloroplasts
      8. Plasma Membrane
      9. Cell Wall
      10. Extracellular Matrix
      11. Flagella and Cilia
      12. Summary
      13. Review Questions
  4. Chapter 5
    1. Unicellular Eukaryotic Parasites
      1. Taxonomy of Protists
    2. Parasitic Helminths
      1. Platyhelminths (Flatworms)
    3. Fungi
      1. Fungal Diversity
    4. Algae
    5. Lichens
      1. Lichen Diversity
      2. Summary
      3. Review Questions
  5. Chapter 6
    1. Viruses
      1. Viral Structures
      2. Classification and Taxonomy of Viruses
    2. The Viral Life Cycle
      1. Transduction
      2. Life Cycle of Viruses with Animal Hosts
      3. Persistent Infections
      4. Life Cycle of Viruses with Plant Hosts
      5. Viral Growth Curve
    3. Isolation, Culture, and Identification of Viruses
      1. Cultivation of Viruses
      2. Detection of a Virus
    4. Viroids, Virusoids, and Prions
      1. Virusoids
      2. Prions
      3. Summary
      4. Review Questions
  6. Chapter 15
    1. Characteristics of Infectious Disease
      1. Classifications of Disease
      2. Periods of Disease
      3. Acute and Chronic Diseases
    2. How Pathogens Cause Disease
      1. Molecular Koch’s Postulates
      2. Pathogenicity and Virulence
      3. Primary Pathogens versus Opportunistic Pathogens
      4. Stages of Pathogenesis
      5. Transmission of Disease
    3. Virulence Factors of Bacterial and Viral Pathogens
      1. Bacterial Exoenzymes and Toxins as Virulence Factors
      2. Virulence Factors for Survival in the Host and Immune Evasion
      3. Viral Virulence
    4. Virulence Factors of Eukaryotic Pathogens
      1. Protozoan Virulence
      2. Helminth Virulence
      3. Summary
      4. Review Questions
  7. Chapter 17
    1. Physical Defenses
      1. Mechanical Defenses
      2. Microbiome
    2. Chemical Defenses
      1. Antimicrobial Peptides
      2. Plasma Protein Mediators
      3. Inflammation-Eliciting Mediators
    3. Cellular Defenses
      1. Granulocytes
      2. Agranulocytes
    4. Pathogen Recognition and Phagocytosis
      1. Pathogen Recognition
      2. Pathogen Degradation
    5. Inflammation and Fever
      1. Chronic Inflammation
      2. Fever
      3. Summary
      4. Review Questions

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