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table of contents
Front Matter
About the Text
OpenStax Preface
Chapter 1
What Our Ancestors Knew
The Iceman Treateth
Early Notions of Disease, Contagion, and Containment
The Birth of Microbiology
A Systematic Approach
Types of Microorganisms
Eukaryotic Microorganisms
Helminths
Viruses
Microbiology as a Field of Study
Summary
Review Questions
Chapter 3
Spontaneous Generation
Disproving Spontaneous Generation
Foundations of Modern Cell Theory
Endosymbiotic Theory
The Germ Theory of Disease
Unique Characteristics of Prokaryotic Cells
The Nucleoid
Plasmids
Ribosomes
Inclusions
Endospores
Plasma Membrane
Cell Wall
Glycocalyces and S-Layers
Filamentous Appendages
Unique Characteristics of Eukaryotic Cells
Nucleus
Ribosomes
Endomembrane System
Peroxisomes
Cytoskeleton
Mitochondria
Chloroplasts
Plasma Membrane
Cell Wall
Extracellular Matrix
Flagella and Cilia
Summary
Review Questions
Chapter 5
Unicellular Eukaryotic Parasites
Taxonomy of Protists
Parasitic Helminths
Platyhelminths (Flatworms)
Fungi
Fungal Diversity
Algae
Lichens
Lichen Diversity
Summary
Review Questions
Chapter 6
Viruses
Viral Structures
Classification and Taxonomy of Viruses
The Viral Life Cycle
Transduction
Life Cycle of Viruses with Animal Hosts
Persistent Infections
Life Cycle of Viruses with Plant Hosts
Viral Growth Curve
Isolation, Culture, and Identification of Viruses
Cultivation of Viruses
Detection of a Virus
Viroids, Virusoids, and Prions
Virusoids
Prions
Summary
Review Questions
Chapter 15
Characteristics of Infectious Disease
Classifications of Disease
Periods of Disease
Acute and Chronic Diseases
How Pathogens Cause Disease
Molecular Koch’s Postulates
Pathogenicity and Virulence
Primary Pathogens versus Opportunistic Pathogens
Stages of Pathogenesis
Transmission of Disease
Virulence Factors of Bacterial and Viral Pathogens
Bacterial Exoenzymes and Toxins as Virulence Factors
Virulence Factors for Survival in the Host and Immune Evasion
Viral Virulence
Virulence Factors of Eukaryotic Pathogens
Protozoan Virulence
Helminth Virulence
Summary
Review Questions
Chapter 17
Physical Defenses
Mechanical Defenses
Microbiome
Chemical Defenses
Antimicrobial Peptides
Plasma Protein Mediators
Inflammation-Eliciting Mediators
Cellular Defenses
Granulocytes
Agranulocytes
Pathogen Recognition and Phagocytosis
Pathogen Recognition
Pathogen Degradation
Inflammation and Fever
Chronic Inflammation
Fever
Summary
Review Questions
About This Text
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Microbiology for Allied Health Students